货号:10010567 | 规格:1 ea (100 µg) | 目录价:¥5096 |
产品详情
产品名称:
Acetyl Lysine Monoclonal Antibody (Clone 7F8)
别名:
ACE
产品描述:
Lysine acetylation is an evolutionarily conserved posttranslational modification that is found in prokaryotes and eukaryotes at histone and non-histone protein sites.{53510} Transfer of an acetyl group from acetyl-coenzyme A (acetyl-CoA) to the amino side chain of lysine is catalyzed by lysine acetyltransferases (KATs), including 13 canonical KATs from the GCN5, p300, and MYST families. Acetyl lysine removal is catalyzed by two major groups of lysine deacetylases (KDACs), the zinc-dependent histone deacetylases (HDACs) and the NAD+-dependent sirtuin deacetylases. Histone acetylation is associated with active gene transcription, and dysregulation of histone acetylation is associated with various diseases including cancer, Huntington's and Alzheimer's diseases, and amyotrophic lateral sclerosis (ALS).{53511,53512,53513} Non-histone protein acetylation is linked to various cellular processes including autophagy, DNA replication, lipid storage, mitochondrial fission and fusion, and protein synthesis, among others.{53510} Cayman's Acetyl Lysine Monoclonal Antibody (Clone 7F8) can be used for ELISA, immunocytochemistry (ICC), and Western blot applications.
宿主来源:
Mouse
实验应用:
ELISA, ICC, WB
同种型:
IgG1
免疫原:
Acetylated KLH
克隆号:
7F8
保存温度:
-20
运输温度:
-20
产品形式:
100 µg of ammonium sulfate precipitated monoclonal antibody
有效期:
1095
来源:
Animal/Mouse
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