AChE (eel) Monoclonal Antibody (Clone 5E2)-单抗-ELISA_抗体_蛋白_核苷酸

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AChE (eel) Monoclonal Antibody (Clone 5E2)

品牌：Cayman

官网链接

说明书

折扣/货期

货号：23855

规格：500 µg

目录价：￥5600

产品详情

产品名称:

AChE (eel) Monoclonal Antibody (Clone 5E2)

别名:

Acetylcholinesterase

产品描述:

Acetylcholinesterase (AChE) is a homotetrameric carboxylesterase that is composed of four 70 kDa subunits with each subunit containing a single active site.{42309} It is a product of alternative splicing and can be membrane bound via a glycosyl-phosphatidylinositol anchor in the membrane or a proline-rich membrane anchor (PRIMA) peptide linker for erythrocyte and synaptic AChE, respectively, or soluble in water, with each form demonstrating identical catalytic activity.{42310} AChE is primarily found in red blood cells as well as at neuromuscular junctions and in the brain at cholinergic synapses where it hydrolyzes acetylcholine to acetate and choline to terminate synaptic transmission.{42310,42311} It accelerates amyloid-β (Aβ) fibrillogenesis in vitro and overexpression of AChE accelerates Aβ plaque formation and disease progression in the Tg2576 transgenic mouse model of Alzheimer's disease.{42312} AChE activity is also increased in islets of Langerhans in rats with diabetes induced by streptozotocin (Item No. 13104). Cayman's AChE (eel) Monoclonal Antibody (clone 5E2) can be used for Western blot and ELISA applications. This antibody recognizes AChE at ~72 kDa from electric eel samples.

宿主来源:

Mouse

实验应用:

ELISA and WB

同种型:

IgG2b

免疫原:

Purified native AChE electric eel protein

克隆号:

500

保存温度:

-20