货号:13733 | 规格:1 ea | 目录价:¥6462 |
产品详情
产品名称:
Akt1 (Phospho-Ser473) Monoclonal Antibody (Clone 104A282)
产品描述:
Akt, protein kinase B (PKB), is a serine/threonine kinase which is involved in many cellular signaling pathways and acts as a transducer of many functions initiated by growth factor receptors that activate phosphatidylinositol 3-kinase (PI3-kinase). The major activity of Akt/PKB is to mediate cell survival. Akt/PKB is also believed to be a critical factor in the genesis of cancer, as the tumor suppressor PTEN was found to antagonise PI3 kinase and Akt/PKB kinase activity. Akt/PKB phosphorylation is critical for its activity. The major phosphorylation sites required for Akt activation have been identified as threoinine 308 and serine 473. Serine473 is phosphorylated by MAPKAP kinase 2.
宿主来源:
Mouse
实验应用:
IP and WB
同种型:
IgG2κ
免疫原:
synthetic peptide from human Akt1 containing phospho-serine473
克隆号:
104A282
保存温度:
-20
运输温度:
-20
产品形式:
100 µg of protein G-purified IgG in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide
有效期:
365
来源:
Animal/Mouse
上一个:KCNQ4 Potassium Channel Monoclonal Antibody (Clone N43-6)
下一个:NF-κB (p65) Monoclonal Antibody (Clone 112A1021)
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