Akt1 (Phospho-Ser473) Monoclonal Antibody (Clone 104A282)-单抗-ELISA_抗体_蛋白_核苷酸

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Akt1 (Phospho-Ser473) Monoclonal Antibody (Clone 104A282)

品牌：Cayman

官网链接

说明书

折扣/货期

货号：13733

规格：1 ea

目录价：￥6462

产品详情

产品名称:

Akt1 (Phospho-Ser473) Monoclonal Antibody (Clone 104A282)

产品描述:

Akt, protein kinase B (PKB), is a serine/threonine kinase which is involved in many cellular signaling pathways and acts as a transducer of many functions initiated by growth factor receptors that activate phosphatidylinositol 3-kinase (PI3-kinase). The major activity of Akt/PKB is to mediate cell survival. Akt/PKB is also believed to be a critical factor in the genesis of cancer, as the tumor suppressor PTEN was found to antagonise PI3 kinase and Akt/PKB kinase activity. Akt/PKB phosphorylation is critical for its activity. The major phosphorylation sites required for Akt activation have been identified as threoinine 308 and serine 473. Serine473 is phosphorylated by MAPKAP kinase 2.

宿主来源:

Mouse

实验应用:

IP and WB

同种型:

IgG2κ

免疫原:

synthetic peptide from human Akt1 containing phospho-serine473

克隆号:

104A282

保存温度:

-20