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折扣/货期| 货号：AG-20B-0005-C100 | 规格：100 ug | 目录价：￥4740 |
产品详情
产品名称:
anti-FLIP, mAb (Dave-2)
别名:
I-FLICE; CLARP; CASPER; Usurpin, CASH; FLAME-1
产品描述:
FLIP is an apoptosis regulator protein which functions as a crucial link between cell survival and cell death pathways in mammalian cells and acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. FLIP lacks enzymatic (caspase) activity. FLIP is highly expressed in skeletal muscle, pancreas, heart, kidney, placenta and peripheral blood leukocytes.
实验应用:
IP, WB
靶标/特异性:
Recognizes an epitope (aa 1-200) present in both short (FLIPS) and long (FLIPL) splice variants of human and mouse FLIP.
同种型:
Rat IgG2a
免疫原:
Recombinant human FLIP (aa 1-480).
克隆号:
Dave-2
产品浓度:
1 mg/ml
保存温度:
-20°C
运输温度:
BLUE ICE
产品形式:
liquid
存储溶液:
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
有效期:
Stable for at least 1 year after receipt when stored at -20°C.
产地:
瑞士
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