anti-NQO1 (human), mAb (Skiny-1)-单抗-ELISA_抗体_蛋白_核苷酸_试剂盒-深圳欣博盛生物科技有限公司

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anti-NQO1 (human), mAb (Skiny-1)

品牌：Adipogen

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说明书

折扣/货期

货号：AG-20A-0086-C050	规格：50 ug	目录价：￥1200
货号：AG-20A-0086-C100	规格：100 ug	目录价：￥1920

产品详情

产品名称:

anti-NQO1 (human), mAb (Skiny-1)

别名:

NAD(P)H Dehydrogenase (Quinine) 1 (NQO1); Quinone Reductase 1 (QR1); DT-Diaphorase (DTD); Azoreductase; Phylloquinone Reductase; Menadione Reductase; Dioxin-inducible 1; Disphorase-4 (DIA4); NAD(P)H:Quinone Oxireductase; NAD(P)H:Quinone Oxidoreductase 1

产品描述:

NQO1 is a cytosolic antioxidant flavoprotein that catalyzes the reduction of highly reactive quinone metabolites and their derivatives by using NAD(P)H as an electron donor. Thus NQO1 acts as a detoxyfying enzyme and is involved in the body’s protection against oxidative stress. NQO1 acts as a protein chaperone, one of its targets being p53. In humans NQO1 is expressed at high levels in adipocytes and its expression levels are positively correlated with adiposity, glucose tolerance, and makers of liver dysfunction. Altered expression of NQO1 is associated with Alzheimer’s disease. NQO1 is abnormally elevated in many types of solid tumors and may represent a useful biomarker of pancreatic cancer.

实验应用:

ELISA, WB

靶标/特异性:

Recognizes human NQO1. Detects a band of ~32kDa by Western blot.

同种型:

Mouse IgG2akappa

免疫原:

Recombinant human NQO1.

克隆号:

Skiny-1

产品浓度:

1mg/ml