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折扣/货期| 货号：AG-20B-0001-C100 | 规格：100 ug | 目录价：￥3960 |
产品详情
产品名称:
anti-NS3 (HCV), mAb (1B6)
别名:
Nonstructural Protein 3
产品描述:
The NS3 serine protease, in association with NS4A, is responsible for the cleavages of the Hepatitis C virus protease complexes NS3-NS4A, NS4A-NS4B, NS4B-NS5A and NS5A-NS5B. NS5B is a RNA-dependent RNA polymerase that plays an essential role in the virus replication. Hepatitis C virus protease NS3-NS4A colocalizes with IPS-1/VISA/MAVS/Cardif in the mitochondrial membrane and has been shown to cleave the TLR3 adapter TRIF and Cardif to eliminate the antiviral signaling pathways. NS3-NS4A represents an important target for anti-HCV drugs.
宿主来源:
Purified from concentrated hybridoma tissue culture supernatant.
实验应用:
ICC, WB
靶标/特异性:
Recognizes HCV NS3 (genotype 1a and 1b) (epitope mapped to NS3 aa 160-193), recognizes NS3 alone or the NS3-4A complex. Does not cross-react with HCV NS3 (genotype 2a).
同种型:
Mouse IgG1
免疫原:
Recombinant hepatitis C virus (HCV) NS3 serine protease domain.
克隆号:
1B6
产品浓度:
1mg/ml
保存温度:
-20°C
运输温度:
BLUE ICE
产品形式:
liquid
存储溶液:
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
有效期:
Stable for at least 1 year after receipt when stored at -20°C.
产地:
瑞士
纯度:
>95% (SDS-PAGE)
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