anti-Periostin [OSF-2], mAb (Stiny-1) (preservative free)-单抗-ELISA_抗体_蛋白_核苷酸

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anti-Periostin [OSF-2], mAb (Stiny-1) (preservative free)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-20B-0033PF-C100

规格：100 ug

目录价：￥4800

产品详情

产品名称:

anti-Periostin [OSF-2], mAb (Stiny-1) (preservative free)

别名:

Osteoblast-specific Factor 2; OSF-2; Postn

产品描述:

Periostin is a 90-kDa matricellular protein that consists of a typical signal sequence, followed by a cysteine-rich region, an EMI domain (protein-protein interactions), four tandem fasciclin-like domains that are responsible for integrin binding, and a C-terminal region. Periostin was originally isolated as an osteoblast-specific factor that functions as a cell adhesion molecule for pre-osteoblasts and in osteoblast recruitment, attachment and spreading. Periostin is also involved in many fundamental biological processes such as cell proliferation, cell invasion and angiogenesis. Periostin expression is increased by both transforming growth factor beta1 (TGF-beta1) and bone morphogenetic protein 2 (BMP-2). Changes in periostin expression are commonly detected in various cancers and pre-cancerous conditions, and periostin may be involved in regulating cancer cell activities that contribute to tumorigenesis, cancer progression and metastasis. Periostin has shown to be involved in many aspects of allergic inflammation, such as eosinophil recruitment, airway remodeling, development of a Th2 phenotype and increased expression of inflammatory mediators. It is evaluated as a biomarker for bronchial asthma and airway inflammation.

宿主来源:

Purified from concentrated hybridoma tissue culture supernatant.

实验应用:

ELISA, IHC, WB

靶标/特异性:

Recognizes human and mouse periostin.

同种型:

Mouse IgG1kappa

免疫原:

Full-length human periostin.

克隆号:

Stiny-1