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折扣/货期| 货号：AG-20B-0009-C100 | 规格：100 ug | 目录价：￥5040 |
产品详情
产品名称:
anti-RIG-I, mAb (Alme-1)
别名:
RIG-1; Retinoic Acid-inducible Gene 1 Protein; DEAD-box Protein 58; Probable ATP-dependent RNA Helicase DDX58
产品描述:
RIG-I and MDA5 are highly conserved helicases involved in the innate immune response to virus. RIG-I is a member of the DEAD-box RNA helicases and is activated by cytoplasmic dsRNA and 5’-ppp RNA produced during the viral replication. The protein is characterized by a N-terminal region with two caspase recruitment domains (CARD) and a C-terminal region harboring potential ATP-dependent RNA helicase activity. RIG-I recruits the CARD adaptor inducing IFN-beta (Cardif) in a CARD-CARD-dependent manner resulting in NF-kappaB and IRF3 activation.
宿主来源:
Purified from concentrated hybridoma tissue culture supernatant.
实验应用:
IHC, IP, WB
靶标/特异性:
Recognizes human and mouse RIG-I.
同种型:
Mouse IgG1
免疫原:
Recombinant human RIG-I (aa 201-713).
克隆号:
Alme-1
产品浓度:
1mg/ml
保存温度:
-20°C
运输温度:
BLUE ICE
产品形式:
liquid
存储溶液:
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
有效期:
Stable for at least 1 year after receipt when stored at -20°C.
产地:
瑞士
纯度:
>95% (SDS-PAGE)
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