官网链接
折扣/货期| 货号：GTX632013-S | 规格：25μl | 目录价：￥1700 |
| 货号：GTX632013 | 规格：100μl | 目录价：￥4000 |
产品详情
产品名称:
ARID1A antibody [GT3611]
别名:
AT-rich interaction domain 1A , B120 , BAF250 , BAF250a , BM029 , C1orf4 , CSS2 , ELD , MRD14 , OSA1 , P270 , SMARCF1 , hELD , hOSA1
反应种属:
Human, Mouse
宿主来源:
Mouse
实验应用:
ICC/IF, IHC-P, WB
同种型:
IgG1
免疫原:
Recombinant protein encompassing a sequence within the C-terminus region of human ARID1A. The exact sequence is proprietary.
克隆性:
Monoclonal
克隆号:
GT3611
纯化方式:
Affinity purified by Protein G.
偶联:
Unconjugated
产品浓度:
2.61 mg/ml (Please refer to the vial label for the specific concentration.)
阳性对照:
293T
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
242
产品形式:
Liquid
存储溶液:
PBS, no preservative.
产地:
美国
功能与背景:
This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
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