货号:13907 | 规格:1 ea | 目录价:¥6246 |
产品详情
产品名称:
Caspase-1 Monoclonal Antibody (Clone 14F468)
别名:
IL-1β Converting Enzyme
产品描述:
Caspases are a family of cysteine proteases that are key mediators of programmed cell death or apoptosis.{1642} The precursor form of all caspases is composed of a prodomain and large and small catalytic subunits. The active forms of caspases are generated by several stimuli including ligand-receptor interactions, growth factor deprivation and inhibitors of cellular functions. All known caspases require cleavage adjacent to aspartates to liberate one large and one small subunit, which associate into a tetramer to form the active enzyme. Caspase-1 is similar to the cell death gene CED-3 of C. elegans and regulates multiple proinflammatory cytokines, including interleukin-1β and interferon-γ-inducing factor.
宿主来源:
Mouse
实验应用:
IHC (paraffin-embedded sections) and WB
同种型:
IgG1κ
免疫原:
synthetic peptide corresponding to human Caspase-1 within the region of amino acids 371-390
克隆号:
14F468
保存温度:
-20
运输温度:
-20
产品形式:
100 µg of protein G-purified IgG in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide
有效期:
365
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