Caspase-8 Monoclonal Antibody (Clone 90A992)-单抗-ELISA_抗体_蛋白_核苷酸

首页产品中心单抗

Caspase-8 Monoclonal Antibody (Clone 90A992)

品牌：Cayman

官网链接

说明书

折扣/货期

货号：13913

规格：1 ea

目录价：￥6318

产品详情

产品名称:

Caspase-8 Monoclonal Antibody (Clone 90A992)

产品描述:

Caspases are a family of cysteine proteases that are key mediators of programmed cell death or apoptosis.{18384} The precursor form of all caspases is composed of a prodomain and large and small catalytic subunits. The active forms of caspases are generated by several stimuli including ligand-receptor interactions, growth factor deprivation, and inhibitors of cellular functions. All known caspases require cleavage adjacent to aspartates to liberate one large and one small subunit, which associate into an a2b2 tetramer to form the active enzyme. Caspase-8 (FLICE) forms a direct link between the activation of CD95 and the caspase pathway. Overexpression of caspase-8 induces apoptosis, which can be blocked by inhibitors specific for the ICE family.

宿主来源:

Mouse

实验应用:

FC, IHC (paraffin-embedded tissue), and WB

同种型:

IgG1

免疫原:

human caspase-8 amino acids PVETDSEEQP

克隆号:

90A992

保存温度:

-20