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折扣/货期| 货号：GTX640472-S | 规格：25μl | 目录价：￥1700 |
| 货号：GTX640472 | 规格：100μl | 目录价：￥4000 |
产品详情
产品名称:
CCR1 antibody [HL3034]
别名:
C-C motif chemokine receptor 1 , CD191 , CKR-1 , CKR1 , CMKBR1 , HM145 , MIP1aR , SCYAR1
反应种属:
Human
宿主来源:
Rabbit
实验应用:
WB
靶标/特异性:
This antibody was raised against human CCR1 Intracellular domain.
同种型:
IgG
免疫原:
Synthetic peptide encompassing a sequence within the Intracellular domain of human CCR1. The exact sequence is proprietary.
克隆性:
Monoclonal
克隆号:
HL3034
纯化方式:
Affinity purified by Protein A.
偶联:
Unconjugated
产品浓度:
batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
41
产品形式:
Liquid
存储溶液:
PBS, no Preservative.
产地:
美国
功能与背景:
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq, Jul 2008]
产品特点:
Orthogonal, Overexpression, Recombinant antibody
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