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折扣/货期| 货号：GTX629481-S | 规格：25μl | 目录价：￥1700 |
| 货号：GTX629481 | 规格：100μl | 目录价：￥4000 |
产品详情
产品名称:
COL11A2 antibody [GT212]
别名:
collagen type XI alpha 2 chain , DFNA13 , DFNB53 , FBCG2 , HKE5 , OSMEDA , OSMEDB , PARP , STL3
反应种属:
Human, Mouse, Rat
宿主来源:
Mouse
实验应用:
WB
同种型:
IgG1
免疫原:
Recombinant protein encompassing a sequence within the N-terminus region of human COL11A2. The exact sequence is proprietary.
克隆性:
Monoclonal
克隆号:
GT212
纯化方式:
Affinity purified by Protein G.
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
阳性对照:
human COLC11A2-transfected 293T cells (partial fragment) , mouse brain , rat brain
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
172
产品形式:
Liquid
存储溶液:
PBS, no preservative.
产地:
美国
功能与背景:
This gene encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. It is located on chromosome 6 very close to but separate from the gene for retinoid X receptor beta. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Proteolytic processing of this type XI chain produces PARP, a proline/arginine-rich protein that is an amino terminal domain. Mutations in this gene are associated with type III Stickler syndrome, otospondylomegaepiphyseal dysplasia (OSMED syndrome), Weissenbacher-Zweymuller syndrome, autosomal dominant non-syndromic sensorineural type 13 deafness (DFNA13), and autosomal recessive non-syndromic sensorineural type 53 deafness (DFNB53). Three transcript variants encoding different isoforms have been identified for this gene. A pseudogene is located nearby on chromosome 6. [provided by RefSeq]
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