货号:20198 | 规格:50 µg | 目录价:¥4410 |
产品详情
产品名称:
COX-2 Monoclonal Antibody (Clone 12C10)
别名:
Cyclooxygenase-2|PGHS-2|Prostaglandin H Synthase 2
产品描述:
Cyclooxygenase 2 (COX-2) is a bifunctional enzyme that exhibits both COX and peroxidase activities and catalyzes the first step in the biosynthesis of prostaglandins, thromboxanes, and prostacyclins.{500,501} The COX component converts arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) to the hydroperoxy endoperoxide prostaglandin G2 (PGG2; Item No. 17010), and the peroxidase component reduces the endoperoxide to the corresponding alcohol PGH2 (Item No. 17020). COX2 expression is induced by a variety of stimuli, including phorbol esters, LPS, and cytokines and is responsible for the biosynthesis of PGs under acute inflammatory conditions.{54420,14766} Thus, COX-2 has been the focus of attention for nonsteroidal anti-inflammatory drug (NSAID) development. Cayman's COX-2 Monoclonal Antibody (Clone 12C10) can be used for ELISA, flow cytometry (FC), immunofluorescence (IF), and Western blot (WB) applications. The antibody recognizes a unique C-terminal region of COX-2 that is not present in COX-1, specifically detecting COX-2 at 72 kDa from human, mouse, and ovine samples.
宿主来源:
Mouse
实验应用:
ELISA, FC, IF, WB
同种型:
IgG1
免疫原:
Synthetic peptide from the C-terminal region of mouse COX-2
克隆号:
12C10
保存温度:
-20
运输温度:
-20
产品形式:
50 µg of protein G-purified IgG
有效期:
1095
您可能感兴趣的产品
IL18 antibody [HL2938]
货号:GTX640322-S
Human Parechovirus 1+3 VP3 antibody [HL2443]
货号:GTX640154-S
C3a Receptor antibody [HL2855]
货号:GTX640126-S
CCR2 antibody [HL2838]
货号:GTX640109-S
TIGIT antibody [HMV322] HistoMAX™
货号:GTX639946-S
PD-L1 antibody [H302] HistoMAX™
货号:GTX639925-S
FSH Receptor antibody [HL2784]
货号:GTX639652-S
P2X5 antibody [HL2773]
货号:GTX639638-S
促销活动
相关产品推荐
5-methyl-2'-deoxy Cytidine ELISA Monoclonal Antibody
货号:489332
Prostaglandin E2 ELISA Monoclonal Antibody
货号:414013
11-dehydro Thromboxane B2 Monoclonal Antibody
货号:419512
Prostaglandin D2 ELISA Monoclonal Antibody
货号:412032
Prostaglandin D2 Express ELISA Monoclonal Antibody
货号:412042
Vitamin D ELISA Monoclonal Antibody
货号:401052