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折扣/货期| 货号：35662-1 mg | 规格：1 mg | 目录价：￥350 |
| 货号：35662-10 mg | 规格：10 mg | 目录价：￥2450 |
| 货号：35662-25 mg | 规格：25 mg | 目录价：￥5250 |
| 货号：35662 | 规格：5 mg | 目录价：￥1316 |
产品详情
产品名称:
GBR 12783 (hydrochloride)
别名:
Lu 2-098|MW-486
产品描述:
GBR 12783 is a dopamine uptake inhibitor (IC50 = 13 nM in rat striatal synaptosomes).{51540} It is selective for inhibition of dopamine uptake over norepinephrine or serotonin (5-HT) uptake (IC50s = 230 and 1,100 nM in rat hypothalamic and striatal synaptosomes, respectively). GBR 12783 (10 mg/kg, i.p.) improves learning and memory in the passive avoidance test in rats, an effect that can be blocked by the anticholinergic agent scopolamine.{51541} It increases locomotor activity, reduces pentobarbital-induced sleep duration, and decreases immobility time in the forced swim test, in mice.{51542} GBR 12783 (10 mg/kg) inhibits catalepsy induced by the antipsychotic haloperidol (Item No. 12014) in rats.
保存温度:
-20
运输温度:
-20
预期分子量:
485.5
产品形式:
A solid
有效期:
1460
纯度:
≥98%
CAS号:
67469-75-4
分子式:
C28H32N2O • 2HCl
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