货号:V9404SAF-100UG | 规格:100 ug | 目录价:¥6176.1 |
产品详情
产品名称:
Granzyme B Antibody
产品描述:
Granzyme B is a member of the granule serine protease family stored specifically in NK cells or cytotoxic T cells. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface antigens, usually peptides or proteins resulting from infection by intracellular pathogens. Granzyme B is crucial for the rapid induction of target cell apoptosis by CTLs in the cell-mediated immune response. Granzyme B is useful as a marker in the identification of NK/T-cell lymphomas. High percentages of cytotoxic T-cells have been shown to be an unfavorable prognostic indicator in Hodgkin s Disease.
反应种属:
Human
宿主来源:
Mouse
实验应用:
WB, IHC-P
同种型:
Mouse IgG1, kappa
免疫原:
A portion of amino acids 73-187 was used as the immunogen for the recombinant GZMB antibody.
克隆性:
Recombinant Mouse Monoclonal
纯化方式:
Protein A/G affinity
保存温度:
Aliquot the recombinant GZMB antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
存储溶液:
1 mg/ml in 1X PBS; BSA free, sodium azide free
产地:
美国
生产商:
NSJ Bio
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