Histone H3K9Me2 Monoclonal Antibody (Clone 9D8)-单抗-ELISA_抗体_蛋白_核苷酸

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Histone H3K9Me2 Monoclonal Antibody (Clone 9D8)

品牌：Cayman

官网链接

说明书

折扣/货期

货号：18072

规格：100 µg

目录价：￥6384

产品详情

产品名称:

Histone H3K9Me2 Monoclonal Antibody (Clone 9D8)

别名:

Dimethylated Histone H3 Lysine 9|Histone H3 containing dimethylated lysine 9

产品描述:

Histone H3 is a nuclear protein and a component of the nucleosome core, a basic unit of chromatin, that is essential for organizing genomic DNA in eukaryotic nuclei.{57056} It is a globular protein that contains an unstructured N-terminal tail that extends outside of the nucleosome core and is subject to various post-translational modifications (PTMs), including methylation, phosphorylation, acetylation, and citrullination.{57056, 53978} Dimethylation of histone H3 at lysine 9 (H3K9Me2) is associated with transcriptional repression.{48220} Heterochromatin protein 1-α (HP1-α), HP1-β, and HP1-γ selectively bind histone H3 N-terminal peptides containing dimethylated lysine 9 over unmodified lysine 9.{20846} High nuclear levels of H3K9Me2 in tumor tissue are associated with decreased disease-specific and disease-free survival in patients with oral and oropharyngeal squamous cell carcinoma.{49115} Cayman’s Histone H3K9Me2 Monoclonal Antibody (Clone 9D8) can be used for ELISA and flow cytometry (FC) applications.

宿主来源:

Mouse

实验应用:

ELISA, FC

同种型:

IgG2bκ

免疫原:

Synthetic peptide from the N-terminal region of human H3K9Me2 conjugated to KLH

克隆号:

9D8

保存温度:

-20