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折扣/货期| 货号：10008206 | 规格：1 ea | 目录价：￥1848 |
产品详情
产品名称:
IGFBP5 Blocking Peptide
别名:
IBP-5 Blocking Peptide|IGF-Binding Protein 5 Blocking Peptide|Insulin-Like Growth Factor-Binding Protein 5 Blocking Peptide
产品描述:
IGFBP5 is a secreted protein that is a critical member of the IGF axis. It binds IGF-1 and restricts it from accessing its cell-surface receptor (IGF-1R). This aids in regulation of cell growth, differentiation, and apoptosis.{14904} IGFBP5 also displays IGF-1 independent transactivational activity in the nucleus.{14903} Some tissues and cell types with higher levels of this protein include kidney, heart, placenta, and skeletal cells.{14902} Expression has also been reported in a variety of cancers, including mammary gland and neuroblastoma.{14904,14899} IGFBP5 (272 amino acids) has a calculated molecular weight of 30.6 kDa. Reported glycosylation and phosphorylation sites may explain the band migration to 33 kDa.{14904,14901} Cayman’s IGFBP5 polyclonal antibody is directed against a synthetic peptide sequence that partially overlaps the IGFBP5 region identified as a nuclear localization signal.{14903}
保存温度:
-20
运输温度:
-20
产品形式:
200 µg of peptide in 200 µl of TBS, pH 7.4, containing 0.1% BSA and 0.02% sodium azide
有效期:
1095
上一个:Serum Retinol Binding Protein 4 Blocking Peptide
下一个:Adipose Triglyceride Lipase Blocking Peptide
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