IgG Fab (mouse) Monoclonal Antibody (Clone RMG05)-单抗-ELISA_抗体_蛋白_核苷酸

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IgG Fab (mouse) Monoclonal Antibody (Clone RMG05)

品牌：Cayman

官网链接

说明书

折扣/货期

货号：21780

规格：100 µg

目录价：￥6832

产品详情

产品名称:

IgG Fab (mouse) Monoclonal Antibody (Clone RMG05)

别名:

Immunoglobulin G

产品描述:

Immunoglobulin G (IgG) is a member of the immunoglobulin superfamily of glycoproteins that plays a central role in the adaptive immune response.{28520} It is produced by B cells and later secreted by plasma cells and is the most abundant circulating antibody in human and mouse serum.{28520,55170,55174} IgG consists of two heavy chains of approximately 50 kDa each and two light chains of approximately 25 kDa each.{28520} The heavy chains are linked together by disulfide bonds to form an Fc region and also combine with the light chains to form the Fab region, which mediate receptor and antigen binding, respectively.{55171} IgG is produced following IgM class-switching in response to infection and is involved in numerous humoral host defense responses, including antibody-dependent cell-mediated cytotoxicity (ADCC), toxin neutralization, and pathogen opsonization.{55170} IgG exists as four isotypes in mice: IgG1, IgG2b, IgG3, and, in a strain-specific manner, IgG2a or IgG2c.{55172,53858} Formulations containing humanized, chimeric, or murine IgG monoclonal antibodies have been used in the treatment of inflammatory diseases, such as ulcerative colitis, rheumatoid arthritis, and asthma, as well as cancer.{55173} Cayman’s IgG Fab (mouse) Monoclonal Antibody (Clone RMG05) can be used for ELISA applications. The antibody recognizes the Fab region of IgG from mouse samples.

宿主来源:

Goat

实验应用:

ELISA

同种型:

IgG

免疫原:

Mouse IgG

克隆号:

RMG05

保存温度:

-20