Influenza A H1N1 (Swine Flu 2009) HA Monoclonal Antibody (Clone 9G1G8)-抗病毒抗体-ELISA_抗体_蛋白_核苷酸

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Influenza A H1N1 (Swine Flu 2009) HA Monoclonal Antibody (Clone 9G1G8)

品牌：Cayman

官网链接

说明书

折扣/货期

货号：39541-100 µl	规格：100 µl	目录价：￥5274
货号：39541	规格：20 µl	目录价：￥1620

产品详情

产品名称:

Influenza A H1N1 (Swine Flu 2009) HA Monoclonal Antibody (Clone 9G1G8)

别名:

Influenza A H1N1 (Swine Flu 2009) Hemagglutinin

产品描述:

Influenza A H1N1 HA is a type I membrane glycoprotein involved in receptor binding and virus-host cell fusion.{69220,69221} It is produced as a precursor protein, HA0, which is composed of a stalk and head domain and forms homotrimers on the viral surface.{69222,69220} The HA0 precursor is cleaved into subunits, HA1 and HA2, which are responsible for host cell surface receptor binding and endosomal membrane fusion, respectively, and this cleavage is required for endosomal fusion.{69220} For influenza A and influenza B, which are low pathogenic influenza viruses, cleavage occurs via trypsin-like proteases, such as transmembrane serine protease 2 (TMRPSS2), which is essential for influenza A HA, but not influenza B HA, cleavage.{69223,69224,69225} Cleaved influenza A H1N1 HA binds to terminal α2,6- or α2,3-sialic acids on glycoproteins or glycolipids on the host cell surface via the receptor-binding domain in the HA1 subunit, which triggers endocytosis of the virus and trafficking of the vesicle into the endosome.{69222,69226,69227} The low pH environment of the endosome triggers viral rearrangement into a prefusion conformation, and the HA2 subunit facilitates fusion with the endosomal membrane to release viral ribonucleoproteins into the cytosol where they are relocated to the nucleus for viral replication.{69222} Cayman’s Influenza A H1N1 (Swine Flu 2009) HA Monoclonal Antibody (Clone 9G1G8) can be used for ELISA and Western blot (WB) applications.

宿主来源:

Mouse

实验应用:

ELISA, WB

同种型:

IgG2b

免疫原:

Recombinant influenza A H1N1 (Swine Flu 2009) HA

克隆号:

9G1G8

保存温度:

运输温度: