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折扣/货期| 货号：39813-10 mg | 规格：10 mg | 目录价：￥1218 |
| 货号：39813-25 mg | 规格：25 mg | 目录价：￥2786 |
| 货号：39813 | 规格：5 mg | 目录价：￥938 |
产品详情
产品名称:
Ipamorelin (acetate)
别名:
Aib-His-D-2-Nal-D-Phe-Lys-NH2|NNC 26-0161
产品描述:
Ipamorelin is a pentapeptide growth hormone secretagogue (GHS) and GHS receptor 1a (GHS-R1a) agonist.{51514,51515} It binds to COS-7 cells expressing GHS-R1a (Ki = 63.4 nM), induces inositol-1,4,5-triphosphate (IP3) accumulation in BHK cells expressing GHS-R1a (EC50 = 46.9 nM), and induces GH release in primary rat pituitary cells (EC50 = 1.3 nM).{51514} Ipamorelin increases plasma levels of GH in rats and pigs (ED50s = 80 and 2.3 nmol/kg, respectively) but does not increase plasma levels of follicle-stimulating hormone (FSH), luteinizing hormone (LH), prolactin, or thyroid stimulating hormone (TSH) in pigs when administered at a dose of 420 nmol/kg.{51515} It increases gastric emptying in a rat model of postoperative ileus induced by laparotomy and intestinal manipulation when administered at doses of 0.014 or 0.14 µmol/kg.{51516} Ipamorelin (18-450 µg/animal) increases body weight and longitudinal bone growth in rats.{51517}
保存温度:
-20
运输温度:
-20
预期分子量:
711.9
产品形式:
A solid
有效期:
1460
纯度:
≥98%
分子式:
C38H49N9O5 • XC2H4O2
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