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折扣/货期| 货号：9001953 | 规格：100 µg | 目录价：￥8414 |
产品详情
产品名称:
JMJD2C tudor domain (human, recombinant)
别名:
GASC-1 Protein|JmjC Domain-containing Histone Demethylation Protein 3C|Jumonji Domain-containing Protein 2C|KDM4C|Lysine-specific Demethylase 4C
产品描述:
Tudor domains are small protein structural motifs of ~50 amino acids related to the “royal family” of methyl readers, which also includes chromo, MBT, PWWP, and Agenet-like domains.{22297, 22331} Tudor domains occur either alone, in tandem, or with other domains and are found in many proteins that are involved in RNA metabolism, germ cell development, transposon silencing, DNA damage response, histone modification, and chromatin remodeling.{22332} The tudor domains recognize symmetric methylated arginine or methylated lysine residues.{18035,22333,22334,22335} JMJD2C is an α-ketoglutarate-dependent Fe (II) oxygenase that catalyzes the demethylation of trimethylated histone H3 at lysine residues 9 and 36 (H3K9me3 and H3K36me3).{29029} This protein product contains the tandem tudor domains of JMJD2C.
保存温度:
-80
运输温度:
-80
产品形式:
50 mM Tris, pH 7.5, containing 150 mM sodium chloride and 20% glycerol
有效期:
180
来源:
Animal/Rabbit
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