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折扣/货期| 货号：90290-1 mg | 规格：1 mg | 目录价：￥448 |
| 货号：90290-10 mg | 规格：10 mg | 目录价：￥2240 |
| 货号：90290-5 mg | 规格：5 mg | 目录价：￥1624 |
| 货号：90290 | 规格：50 mg | 目录价：￥9576 |
产品详情
产品名称:
MEDICA 16
别名:
FA 20:0;O2
产品描述:
MEDICA 16 is a G protein-coupled receptor 40 (GPR40) agonist and GPR120 partial agonist.{69174} MEDICA 16 induces intracellular calcium mobilization in cells expressing GPR40 or GPR120 in a concentration-dependent manner. It induces ERK activation in cells expressing GPR40 or GPR120 when used at a concentration of 100 µM. MEDICA 16 also inhibits ATP citrate lyase (Kis = 40 and 200 µM for the oxidized and reduced enzyme, respectively).{2689} Chronic dietary administration of MEDICA 16 (0.25% w/w) decreases liver acetyl-CoA carboxylase (ACC) and AMP-activated protein kinase (AMPK) levels in a model of insulin resistance using JCR:LA-cp rats, which lack functioning leptin receptors.{69175} MEDICA 16 (0.25% w/w in the diet) reduces plasma insulin levels, decreases fasting plasma triacylglycerol levels, and delays the onset of hyperinsulinemia in JCR:LA-cp rats.{69176}
保存温度:
-20
运输温度:
-20
预期分子量:
342.5
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
CAS号:
87272-20-6
分子式:
C20H38O4
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