官网链接
折扣/货期| 货号：V9351-100UG | 规格：100 ug | 目录价：￥6176.1 |
| 货号：V9351-20UG | 规格：20 ug | 目录价：￥2725.1 |
产品详情
产品名称:
MPO Antibody / Myeloperoxidase
产品描述:
The heme protein myeloperoxidase (MPO) is a major component of azurophilicgranules of neutrophils and polymorphonuclear leukocytes. Optimal oxygen-dependent microbiocidal activity depends on MPO as the critical enzyme forthe generation of hypochlorous acid and other toxic oxygen products. TheMPO precursor is synthesized during the promyelocytic stage of myeloid dif-ferentiation and is subsequently processed and transported intracellularly tothe lysosomes. The precursor undergoes cotranslational N-linked glycosyla-tion to produce a glycoprotein. Glucosidases in the endoplasmic reticulum(ER) or early cisGolgi convert the pro-MPO to a form which is sorted into aprelysosomal compartment, which undergoes final proteolytic maturation tonative MPO, a pair of heavy-light protomers. In normal neutrophils, MPO isexpressed as a dimer. Calreticulin, a calcium-binding protein residing in theER, interacts specifically with fully glycosylated apopro-MPO. iMPO mRNA isabundant in human promyelocytic HL-60 and mouse myeloid leukemia NFS-60cells. MPO is expressed at high levels in circulating neutrophils and mono-cytes but is not detectable in microglia, brain-specific macrophages or normalbrain tissue.MPO, which has a molecular weight of approximately 140 kD, is homodimer that can be split into two halves that still have enzymatic activity. These hemi-MPOmonomersconsist of a 59-kD alpha chainand a 13.5-kD beta chain.
反应种属:
Human
宿主来源:
Rabbit
实验应用:
WB, IHC-P
同种型:
Rabbit IgG, kappa
免疫原:
A portion of amino acids 150-250 of human Myeloperoxidase protein was used as the immunogen for the Myeloperoxidase antibody.
克隆性:
Polyclonal (rabbit origin)
纯化方式:
Protein A/G affinity
保存温度:
Aliquot the Myeloperoxidase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
存储溶液:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
产地:
美国
生产商:
NSJ Bio
您可能感兴趣的产品
SARS-CoV-2 (COVID-19) nsp1 antibody
货号：GTX135612-S
Synapsin II antibody
货号：GTX135310-S
DLST antibody
货号：GTX134855-S
IGF2BP1 antibody
货号：GTX134816-S
SMCR8 antibody
货号：GTX134785-S
3-Methoxytyramine antibody
货号：GTX134712-S
Estrogen Receptor beta antibody
货号：GTX134663-S
Caspase 1 p10 subunit antibody
货号：GTX134551-S
促销活动
相关产品推荐
MPO Antibody / Myeloperoxidase
货号：V9351SAF-100UG
CEA Antibody / Carcinoembryonic Antigen
货号：V9164-100UG
CEA Antibody / Carcinoembryonic Antigen
货号：V9164SAF-100UG
TRP1 / Tyrosinase-Related Protein-1 Antibody
货号：V8898-100UG
TRP1 / Tyrosinase-Related Protein-1 Antibody
货号：V8898SAF-100UG
AMACR / p504S Antibody (Prostate Cancer Marker)
货号：V8877-100UG
