NF-κB (p50) Monoclonal Antibody (Clone 2J10D7)-单抗-ELISA_抗体_蛋白_核苷酸

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NF-κB (p50) Monoclonal Antibody (Clone 2J10D7)

品牌：Cayman

官网链接

说明书

折扣/货期

货号：13755

规格：1 ea

目录价：￥6336

产品详情

产品名称:

NF-κB (p50) Monoclonal Antibody (Clone 2J10D7)

产品描述:

NF-κB is a transcription factor activated by various extra and intracellular stimuli such as cytokines, UV radiation, stress, injury, and by bacterial and viral products. It is involved in regulation of various cellular events including cell growth, differentiation, proliferation, apoptosis, and inflammation. NF-κB1 (p50), a 50 kDa functional sub-unit of NF-κB, is a member of the Rel protein family. It is synthesized as a p105 precursor protein and consists of an N-terminal conserved RHD-region containing a nuclear localization signal, DNA-binding and dimerization domains. NF-κB (p50) forms homodimers or heterodimerizes with p65, forming the functional NF-κB factor. NF-κB (p50) directs the nuclear translocation of NF-κB and is instrumental in its DNA-binding. A pathological role of NF-κB has been suggested in AIDS, hematogenic cancer cell metastasis, and rheumatoid arthritis.

宿主来源:

Mouse

实验应用:

IHC and WB

同种型:

IgG1κ

免疫原:

a portion of amino acids 150-200 of human NF-κB (p50)

克隆号:

2J10D7

保存温度:

-20