货号:13755 | 规格:1 ea | 目录价:¥6336 |
产品详情
产品名称:
NF-κB (p50) Monoclonal Antibody (Clone 2J10D7)
产品描述:
NF-κB is a transcription factor activated by various extra and intracellular stimuli such as cytokines, UV radiation, stress, injury, and by bacterial and viral products. It is involved in regulation of various cellular events including cell growth, differentiation, proliferation, apoptosis, and inflammation. NF-κB1 (p50), a 50 kDa functional sub-unit of NF-κB, is a member of the Rel protein family. It is synthesized as a p105 precursor protein and consists of an N-terminal conserved RHD-region containing a nuclear localization signal, DNA-binding and dimerization domains. NF-κB (p50) forms homodimers or heterodimerizes with p65, forming the functional NF-κB factor. NF-κB (p50) directs the nuclear translocation of NF-κB and is instrumental in its DNA-binding. A pathological role of NF-κB has been suggested in AIDS, hematogenic cancer cell metastasis, and rheumatoid arthritis.
宿主来源:
Mouse
实验应用:
IHC and WB
同种型:
IgG1κ
免疫原:
a portion of amino acids 150-200 of human NF-κB (p50)
克隆号:
2J10D7
保存温度:
-20
运输温度:
-20
产品形式:
100 µg of protein G-purified IgG in 200 µl PBS containing 0.2% gelatin and 0.05% sodium azide
有效期:
365
上一个:NF-κB (p65) Monoclonal Antibody (Clone 112A1021)
下一个:NF-κB (p65) Monoclonal Antibody - Biotinylated (Clone 112A1021)
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