货号:39074-1 g | 规格:1 g | 目录价:¥4732 |
货号:39074 | 规格:500 mg | 目录价:¥2492 |
产品详情
产品名称:
PAMAM Dendrimer G4.0 Amine (water solution)
别名:
PAMAM G4.0|Polyamidoamine Dendrimer G4.0
产品描述:
PAMAM dendrimer G4.0 amine (PAMAM G4.0) is a polyamidoamine (PAMAM) dendrimer with amine termini that has been used as a drug delivery system in vivo.{51536,72161} It is approximately 45 Å in diameter and has 64 surface groups.{51536} It inhibits fibril formation by α-synuclein in a cell-free assay when used at concentrations of 1 and 2 µM.{72162} PAMAM G4.0 is active against E. coli (IC50 = 3.8 µg/ml) and toxic to zebrafish embryos, inducing mortality at 120 hours post-fertilization when used at concentrations ranging from 0.5 to 20 µM.{51536,51537} PAMAM G4.0 (100 and 300 mg/kg) in complex with the topoisomerase I inhibitor camptothecin (Item No. 11694) increases the oral bioavailability of camptothecin in mice without inducing gastrointestinal toxicity.{51539} PEG-modified PAMAM G4.0 in complex with folic acid (Item No. 20515), 5-fluorouracil (5-FU; Item No. 14416), and the imaging agent technetium-99m (PEG-PAMAM G4-FA-5FU-99mTc) localizes to the tumor, as well as the liver and spleen, in a 4T1 murine mammary tumor model.{72161}
保存温度:
-20
运输温度:
-20
预期分子量:
14214.2
产品形式:
A solution in water
有效期:
730
CAS号:
163442-67-9
分子式:
[NH2(CH2)2NH2]:(G=4);dendri PAMAM(NH2)64
您可能感兴趣的产品
Human Ovary (Normal) tissue slides
货号:GTX03349
Trident High-Efficiency Exosome Precipitation Reagent
货号:GTX00835
SARS-CoV-2 (COVID-19) Spike (Omicron BA.4 / BA.5) FFPE 293T Cell Pellet Block
货号:GTX437396
Alzheimer brain : hippocampus tissue slides
货号:GTX24583
Human Brain: Hippocampus (Normal) tissue slides
货号:GTX24305
Human Brain: Hippocampus (Parkinson's Disease) tissue slides
货号:GTX22222
Mouse Tissue Array III - Normal Tissues
货号:GTX03659
Tween 20
货号:GTX03634
促销活动