PAMAM Dendrimer G4.0 Amine (water solution)-其他-ELISA_抗体_蛋白_核苷酸

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PAMAM Dendrimer G4.0 Amine (water solution)

品牌：Cayman

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折扣/货期

货号：39074-1 g	规格：1 g	目录价：￥4732
货号：39074	规格：500 mg	目录价：￥2492

产品详情

产品名称:

PAMAM Dendrimer G4.0 Amine (water solution)

别名:

PAMAM G4.0|Polyamidoamine Dendrimer G4.0

产品描述:

PAMAM dendrimer G4.0 amine (PAMAM G4.0) is a polyamidoamine (PAMAM) dendrimer with amine termini that has been used as a drug delivery system in vivo.{51536,72161} It is approximately 45 Å in diameter and has 64 surface groups.{51536} It inhibits fibril formation by α-synuclein in a cell-free assay when used at concentrations of 1 and 2 µM.{72162} PAMAM G4.0 is active against E. coli (IC50 = 3.8 µg/ml) and toxic to zebrafish embryos, inducing mortality at 120 hours post-fertilization when used at concentrations ranging from 0.5 to 20 µM.{51536,51537} PAMAM G4.0 (100 and 300 mg/kg) in complex with the topoisomerase I inhibitor camptothecin (Item No. 11694) increases the oral bioavailability of camptothecin in mice without inducing gastrointestinal toxicity.{51539} PEG-modified PAMAM G4.0 in complex with folic acid (Item No. 20515), 5-fluorouracil (5-FU; Item No. 14416), and the imaging agent technetium-99m (PEG-PAMAM G4-FA-5FU-99mTc) localizes to the tumor, as well as the liver and spleen, in a 4T1 murine mammary tumor model.{72161}

保存温度:

-20

运输温度:

-20

预期分子量:

14214.2

产品形式:

A solution in water

有效期:

730

CAS号:

163442-67-9