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折扣/货期| 货号：13557 | 规格：1 ea | 目录价：￥6462 |
产品详情
产品名称:
PARP (Cleaved) Monoclonal Antibody
产品描述:
The poly(ADP-ribose) polymerase (PARP) is involved in cell recovery from DNA damage, such as methylation of N3-adenine, which activates the base excision repair process. PARP is a 116 kDa nuclear chromatin-associated enzyme that is cleaved during apoptosis by caspase-3 into a 24 kDa fragment containing the DNA binding domain and an 89 kDa fragment containing the catalytic and automodification domains. The 24 kDa fragment irreversibly binds to DNA and may contribute to the irreversibility of apoptosis by blocking the access of DNA repair enzymes to DNA strand breaks.
宿主来源:
Mouse
实验应用:
WB and FC (intracellular)
同种型:
IgG2bκ
免疫原:
synthetic peptide containing amino acids near the 214/215 cleavage site of human PARP
保存温度:
-20
运输温度:
-20
产品形式:
100 µg protein G-purified IgG in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide
有效期:
365
来源:
Animal/Mouse
上一个:Histone H3 (Phospho-Ser28) Monoclonal Antibody (Clone 117C826)
下一个:Toll-Like Receptor 2 Monoclonal Antibody (Clone TL2.1)
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