PCSK9 (human) Monoclonal Antibody (Clone 15A6)-单抗-ELISA_抗体_蛋白_核苷酸

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PCSK9 (human) Monoclonal Antibody (Clone 15A6)

品牌：Cayman

官网链接

说明书

折扣/货期

货号：10218

规格：1 ea (500 µg)

目录价：￥4410

产品详情

产品名称:

PCSK9 (human) Monoclonal Antibody (Clone 15A6)

别名:

NARC-1|Proprotein Convertase Subtilisin/Kexin Type 9

产品描述:

Proprotein convertase subtilisin kexin 9 (PCSK9) is a member of the subtilisin serine protease family with an important role in lipoprotein metabolism.{13178} Gain-of-function mutations in the PCSK9 gene are associated with autosomal dominant hypercholesterolemia which is characterized by an increase in low-density lipoprotein (LDL) cholesterol levels.{13158} PCSK9 overexpression in wild-type mice doubles the plasma total cholesterol, possibly through accelerated LDL receptor degredation.{13178,13176} PCSK9 mRNA is detected in various tissues such as liver, kidney, lung, spleen, jejunum, ileum, colon, and muscle with the highest expression in the liver.{13136} Human PCSK9 precursor is 692 amino acids in length with an estimated molecular weight of 74 kDa. This proprotein is self-cleaved to form a mature protein at around 63 kDa in the Golgi body.{13177}

宿主来源:

Mouse

实验应用:

同种型:

IgG1

免疫原:

Purified human recombinant PCSK9

克隆号:

15A6

保存温度:

-20

运输温度: