PRMT6 (human recombinant; baculovirus expressed)-其他酶-ELISA_抗体_蛋白_核苷酸

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PRMT6 (human recombinant; baculovirus expressed)

品牌：Cayman

官网链接

说明书

折扣/货期

货号：13866

规格：50 µg

目录价：￥6762

产品详情

产品名称:

PRMT6 (human recombinant; baculovirus expressed)

别名:

Histone Arginine N-methyltransferase PRMT6|HRMT1L6|Protein Arginine Methyltransferase 6

产品描述:

Protein arginine methyltransferases (PRMTs) are a family of enzymes with highly conserved catalytic domains that catalyze the transfer of a methyl group from S-adenosyl-L-methionine to a specific arginine residue in a target protein. PRMT6 is a nuclear type-1 PRMT, catalyzing the formation of ω-NG-monomethylarginine and asymmetric ω-NG,NG-dimethylarginine on both histone and non-histone targets.{20285,20245,20284} Histone H3 methylation of arginine 2 (H3R2) is a repressive transcriptional mark primarily catalyzed by PRMT6.{20286} H3R2 dimethylation antagonizes the binding of effector proteins sensitive to H3K4 methylation, such as the Mixed Lineage Leukemia complex methyltransferase.{20287} Non-histone targets of PRMT6 include the nuclear high-mobility group protein HMGA1a, a protein important in several processes relating to the maintenance of DNA integrity.{20284}

保存温度:

-80

运输温度:

-80

产品形式:

50 mM Tris-HCl, pH 8.0, with 150 mM sodium chloride and 20% glycerol

有效期:

365

纯度:

≥60%

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