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产品名称:
AChE antibody [HL1102]
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别名:
acetylcholinesterase (Cartwright blood group) , ACEE , ARACHE , N-ACHE , YT
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产品描述:
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反应种属:
Cat, Human, Mouse, Rat
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宿主来源:
Rabbit
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实验应用:
ICC/IF, IHC-P, WB
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靶标/特异性:
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同种型:
IgG
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推荐稀释度:
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免疫原:
Recombinant protein encompassing a sequence within the C-terminus region of human AChE. The exact sequence is proprietary.
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免疫原种属:
Human
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克隆性:
Monoclonal
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克隆号:
HL1102
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纯化方式:
Affinity purified by Protein A.
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偶联:
Unconjugated
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产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
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表达系统:
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阳性对照:
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保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
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运输温度:
4°C
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细胞定位:
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预期分子量:
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产品形式:
Liquid
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存储溶液:
PBS, no preservative.
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有效期:
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产地:
美国
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外观:
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生产商:
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功能与背景:
Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally. [provided by RefSeq, Jul 2008]
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URL:
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灵敏度:
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样本类型:
PBS, no preservative.
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