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产品名称:
EBAG9 Antibody / RCAS1
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别名:
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产品描述:
EBAG9 (Estrogen receptor-binding fragment-associated gene 9 protein), also known as RCAS1, is an estrogen-transcribed protein. Soluble and membranous RCAS1 proteins may play a role in the immune escape of tumor cells by promoting T lymphocyte inhibition of growth and apoptosis. RCAS1 is expressed in a wide variety of cancers, including uterine, ovarian, and lung cancer cells, and acts as a ligand for a putative receptor present on peripheral lymphocytes. RCAS1 is highly expressed not only in cancer cells but also in non-tumor bile duct cells subject to immune attack. RCAS1 inhibits the in vitro growth of receptor-expressing cells and induces apoptosis, contributing to the ability of tumor cells to evade host immune surveillance. High expression of RCAS1 significantly correlates with tumor progression and with poor outcome for many cancer patients.
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反应种属:
Human
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宿主来源:
Mouse
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实验应用:
IHC-P
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靶标/特异性:
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同种型:
Mouse IgG1, kappa
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推荐稀释度:
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免疫原:
Recombinant full-length human protein was used as the immunogen for the EBAG9 antibody.
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免疫原种属:
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克隆性:
Recombinant Mouse Monoclonal
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克隆号:
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纯化方式:
Protein A/G affinity
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偶联:
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保存温度:
Aliquot the EBAG9 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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产品形式:
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存储溶液:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
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有效期:
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产地:
美国
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样本类型:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
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