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BCOR Antibody / BCL-6 corepressor
品牌： NSJ Bio
产品货号： V5338SAF-100UG
规格： 100 ug

报价：
折后价：

数量： - +
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  • 产品名称:
    BCOR Antibody / BCL-6 corepressor
  • 别名:
  • 产品描述:
    Bcl-6, a transcriptional repressor, can promote or inhibit apoptosis depending on the cell type and also plays an important role in normal immune responses. Bcl-6 negatively regulates NFkB expression, thereby inhibiting NFkB-mediated cellular functions and is frequently found to be deregulated in non-Hodgkin's lymphoma. BCoR (Bcl-6 corepressor) is a 1,755 amino acid protein that associates with histone deacetylases (HDACs) to transcriptionally repress Bcl-6. With ubiquitous expression, BCoR is localized to the nucleus where it interacts with other proteins through its three ANK repeat domains. Mutations in the gene encoding BCoR result in microphthalmia with associated anomalies 2, also known as anophthalmia, which is characterized by variable features, such as renal aplasia, mental retardation, hyospadias, microencephaly and cryptorchidism. There are four isoforms of BCoR which are produced as a result of alternative splicing events.
  • 反应种属:
    Human
  • 宿主来源:
    Mouse
  • 实验应用:
    IHC-P
  • 靶标/特异性:
  • 同种型:
    Mouse IgG2, kappa
  • 推荐稀释度:
  • 免疫原:
    A recombinant partial protein sequence (within amino acids 100-400) from the human protein was used as the immunogen for the BCOR antibody.
  • 免疫原种属:
  • 克隆性:
    Monoclonal (mouse origin)
  • 克隆号:
  • 纯化方式:
    Protein A/G affinity
  • 偶联:
  • 产品浓度:
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    Aliquot the BCOR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 运输温度:
  • 细胞定位:
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  • 产品形式:
  • 存储溶液:
    1 mg/ml in 1X PBS; BSA free, sodium azide free
  • 有效期:
  • 产地:
    美国
  • 外观:
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  • 功能与背景:
  • URL:
  • 灵敏度:
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  • 检测方法:
  • 样本类型:
    1 mg/ml in 1X PBS; BSA free, sodium azide free
  • 产品特点:
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  • 分子式:
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