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产品名称:
GATA3 Antibody
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别名:
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产品描述:
GATA-3 (GATA binding protein 3) is a member of the GATA family of transcription factors. This 50kDa nuclear protein regulates the development and subsequent maintenance of a variety of human tissues, including hematopoietic cells, skin, kidney, mammary gland, and the central nervous system. Among several other roles, GATA-3 involved in luminal cell differentiation in the mammary gland and appears to control a set of genes involved in the differentiation and proliferation of breast cancer. The expression of GATA-3 is associated with the expression of estrogen receptor-alpha (ER) in breast cancer. GATA-3 has been shown to be a novel marker for bladder cancer. The study demonstrated that GATA-3 stained 67% of urothelial Carcinomas, but none of prostate or renal carcinomas.
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反应种属:
Human
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宿主来源:
Rabbit
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实验应用:
IHC-P
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靶标/特异性:
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同种型:
Rabbit IgG, kappa
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推荐稀释度:
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免疫原:
Recombinant full-length human GATA-3 protein was used as the immunogen for the GATA-3 antibody.
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免疫原种属:
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克隆性:
Recombinant Rabbit Monoclonal
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克隆号:
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纯化方式:
Protein A/G affinity
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偶联:
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阳性对照:
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保存温度:
Aliquot the GATA-3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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运输温度:
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产品形式:
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存储溶液:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
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有效期:
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产地:
美国
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样本类型:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
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