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GAD65 Antibody / GAD2
品牌: NSJ Bio
产品货号: V4087SAF-100UG
规格: 100 ug

报价:
折后价:

数量: - +
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
  • 产品名称:
    GAD65 Antibody / GAD2
  • 别名:
  • 产品描述:
    This mAb recognizes a protein of 65kDa, which is identified as glutamic acid decarboxylase 2 (GDA2). It is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. There are two forms of glutamic acid decarboxylases (GAD s) that are found in the brain: GAD2 (also known as GAD65) and GAD1 (also known as GAD67). GAD1 and GAD2 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate-limiting step in the production of GABA (gamma-aminobutyric acid) from L-glutamic acid. Although both GAD s are found in the brain, GAD2 localizes to synaptic vesicle membranes in nerve terminals, while GAD1 is distributed throughout the cell. A pathogenic role for GAD2 is identified in the human pancreas since it has been identified as an autoantibody and an auto-reactive T cell target in insulin-dependent diabetes.
  • 反应种属:
    Human
  • 宿主来源:
    Mouse
  • 实验应用:
    ELISA, WB, IHC-P
  • 靶标/特异性:
  • 同种型:
    Mouse IgG2b, kappa
  • 推荐稀释度:
  • 免疫原:
    A recombinant fragment of human GAD2/GAD65 protein (within amino acids 1-200) was used as the immunogen for the GAD65 antibody.
  • 免疫原种属:
  • 克隆性:
    Monoclonal (mouse origin)
  • 克隆号:
  • 纯化方式:
    Protein A/G affinity
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  • 保存温度:
    Aliquot the GAD65 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 运输温度:
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  • 产品形式:
  • 存储溶液:
    1 mg/ml in 1X PBS; BSA free, sodium azide free
  • 有效期:
  • 产地:
    美国
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  • 样本类型:
    1 mg/ml in 1X PBS; BSA free, sodium azide free
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