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FTH1 Antibody / Ferritin heavy chain
品牌： NSJ Bio
产品货号： V4170SAF-100UG
规格： 100 ug

报价：
折后价：

数量： - +
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  • 产品名称:
    FTH1 Antibody / Ferritin heavy chain
  • 别名:
  • 产品描述:
    Mammalian ferritins consist of 24 subunits made up of 2 types of poly-peptide chains, ferritin heavy chain and ferritin light chain, which each have unique functions. Ferritin heavy chains catalyze the first step in iron storage, the oxidationof FeI(II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe(III). The most prominent role of mammalian ferritins is to provide iron-buffering capacity to cells. In addition to iron buffering, heavy chain ferritin is also involved in the regulation of thymidine biosynthesis via increased expression of cytoplasmic serine hydroxymethyltransferase, which is a limiting factor in thymidylate synthesis in MCF-7 cells. Light chain ferritin is involved in cataracts by at least two mechanisms: hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed; and oxidative stress, an important factor in the development of aging-related cataracts.
  • 反应种属:
    Human
  • 宿主来源:
    Rabbit
  • 实验应用:
    IHC-P
  • 靶标/特异性:
  • 同种型:
    Rabbit IgG, kappa
  • 推荐稀释度:
  • 免疫原:
    A recombinant human FTH1 protein fragment (within amino acids 58-180) was used as the immunogen for the recombinant Ferritin Heavy Chain antibody.
  • 免疫原种属:
  • 克隆性:
    Recombinant Rabbit Monoclonal
  • 克隆号:
  • 纯化方式:
    Protein A/G affinity
  • 偶联:
  • 产品浓度:
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  • 阳性对照:
  • 保存温度:
    Aliquot the recombinant Ferritin Heavy Chain antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 运输温度:
  • 细胞定位:
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  • 产品形式:
  • 存储溶液:
    1 mg/ml in 1X PBS; BSA free, sodium azide free
  • 有效期:
  • 产地:
    美国
  • 外观:
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  • 检测方法:
  • 样本类型:
    1 mg/ml in 1X PBS; BSA free, sodium azide free
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  • 分子式:
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