Alpha B Crystallin Antibody / CRYAB - 深圳欣博盛生物科技有限公司

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Alpha B Crystallin Antibody / CRYAB

品牌： NSJ Bio

产品货号： V4180-100UG

规格： 100 ug

报价：

折后价：

数量： - +

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产品名称:

Alpha B Crystallin Antibody / CRYAB
别名:
产品描述:

Crystallins are the major proteins of the vertebrate eye lens, where they maintain the transparency and refractive index of the lens. Crystallins are divided into Alpha, Beta and Gamma families, and the Beta- and Gamma-crystallins also compose a superfamily. Crystallins usually contain seven distinct protein regions, including four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Alpha-crystallins consist of three gene products, AlphaA-, AlphaB- and AlphaC-crystallin, which are members of the small heat shock protein family (HSP 20). Alpha-crystallins act as molecular chaperones by holding denatured proteins in large soluble aggregates. However, unlike other molecular chaperones, Alpha-crystallins do not renature these proteins. Expression of AlphaA-crystallin is restricted to the lens and defects of this gene cause the development of autosomal dominant congenital cataracts (ADCC). The human AlphaB-crystallin gene product is expressed in many tissues, including lens, heart and skeletal muscle. Elevated expression of AlphaB-crystallin is associated with many neurological diseases, and a missense mutation in this gene has co-segregated in a family with a Desmin-related myopathy.
反应种属:

Human
宿主来源:

Mouse
实验应用:

IHC-P
靶标/特异性:
同种型:

Mouse IgG1, kappa
推荐稀释度:
免疫原:

Recombinant human full-length CRYAB protein was used as the immunogen for the Crystallin Alpha B antibody.
免疫原种属:
克隆性:

Monoclonal (mouse origin)
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纯化方式:

Protein A/G affinity
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保存温度:

Aliquot the Crystallin Alpha B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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存储溶液:

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
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产地:

美国
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0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
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