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CD91 Antibody / LRP1 / A2MR
品牌： NSJ Bio
产品货号： V4303-20UG
规格： 20 ug

报价：
折后价：

数量： - +
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  • 产品名称:
    CD91 Antibody / LRP1 / A2MR
  • 别名:
  • 产品描述:
    Members of the LDL receptor gene family, including LDLR (low density lipoprotein receptor), LEP1 (low density lipoprotein related protein), megalin (also designated GP330), VLDLR (very low density lipoprotein receptor) and apoER2 are characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. LRP1, also designated LRP and Alpha-2-Macroglobulin receptor, is an endocytic receptor that mediates the uptake of at least 15 ligands, including Alpha-2-Macroglobulin and apoE. LRP1 is cleaved into a membrane subunit and an extracellular subunit, which remain non-covalently associated. Proper folding and trafficking of LRP1 is facilitated by the receptor-associated protein (RAP), a molecular chaperone. The uptake of all known ligands through LRP1 can be blocked by RAP, which induces a conformational change in the receptor that renders it unable to bind ligands. LRP1, which is expressed in brain, liver and lung, is also implicated in Alzheimer s disease (AD), as the human LRP gene localizes to a potential AD locus on chromosome 12.
  • 反应种属:
    Human
  • 宿主来源:
    Rabbit
  • 实验应用:
    IHC-P
  • 靶标/特异性:
  • 同种型:
    Rabbit IgG, kappa
  • 推荐稀释度:
  • 免疫原:
    A recombinant fragment of human protein was used as the immunogen for the recombinant A2MR antibody.
  • 免疫原种属:
  • 克隆性:
    Recombinant Rabbit Monoclonal
  • 克隆号:
  • 纯化方式:
    Protein A/G affinity
  • 偶联:
  • 产品浓度:
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    Aliquot the recombinant A2MR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 运输温度:
  • 细胞定位:
  • 预期分子量:
  • 产品形式:
  • 存储溶液:
    0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
  • 有效期:
  • 产地:
    美国
  • 外观:
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  • 功能与背景:
  • URL:
  • 灵敏度:
  • 检测范围:
  • 检测方法:
  • 样本类型:
    0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
  • 产品特点:
  • 纯度:
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  • 分子式:
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  • PubChem CID:
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