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产品名称:
IgD Heavy Chain Antibody
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别名:
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产品描述:
Immunoglobulins are four-chain, Y-shaped, monomeric structures comprised of two identical heavy chains and two identical light chains held together through interchain disulfide bonds. The chains form two domains, the Fab (antigen binding) fragment and the Fc (constant) fragment. Immunoglobulin D (IgD) exists as a monomer with delta heavy chains and either kappa or lambda light chains. It plays a biological role as a transmembrane receptor molecule, co-expressed with IgM on the surface of mature/naive B cells. In particular, it is found on spleen B cell surfaces. Compared to IgM, IgD exists in much lower numbers and is not expressed on immature B cells. IgD surface expression on B cells is regulated in part by IL-27. In mice, the inhibition of this immunoglobulin isotype does not cause a significant change to the immune system.
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反应种属:
Human
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宿主来源:
Rabbit
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实验应用:
IHC-P
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靶标/特异性:
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同种型:
Rabbit IgG, kappa
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推荐稀释度:
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免疫原:
A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the recombinant IgD antibody.
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免疫原种属:
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克隆性:
Recombinant Rabbit Monoclonal
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克隆号:
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纯化方式:
Protein A/G affinity
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保存温度:
Aliquot the recombinant IgD antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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产品形式:
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存储溶液:
1 mg/ml in 1X PBS; BSA free, sodium azide free
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有效期:
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产地:
美国
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样本类型:
1 mg/ml in 1X PBS; BSA free, sodium azide free
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