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TPM1 Antibody / Tropomyosin-1 / Alpha Tropomyosin
品牌： NSJ Bio
产品货号： V4387-20UG
规格： 20 ug

报价：
折后价：

数量： - +
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  • 产品名称:
    TPM1 Antibody / Tropomyosin-1 / Alpha Tropomyosin
  • 别名:
  • 产品描述:
    Tropomyosins are a group of structural proteins. Tropomyosins are present in virtually all eukaryotic cells, both muscle and non-muscle, where they bind actin filaments and function to modulate Actin-myosin interaction and stabilize actin filament structure. Tropomyosin Alpha is encoded by the TPM1 gene, which maps to human chromosome 15q22.2 and undergoes alternative splicing to generate at least four isoforms, including skeletal muscle (isoform 1), smooth muscle (isoform 2), fibroblast/TM3 (isoform 3) and isoform 4. Tropomyosin b is encoded by the TPM2 gene, which maps to human chromosome 9p13.3 and undergoes alternative splicing to generate three isoforms, including skeletal muscle (isoform 1), non-muscle/fibroblast TM36/epithelial TMe1 (isoform 2) and non-muscle (isoform 3). Troponin I binds Tropomyosin at a specific region and the association of Tropomyosin-Troponin with actin filaments may increase the rigidity of actin filaments. Tropomyosin also interacts with caldesmon to regulate smooth muscle contraction.
  • 反应种属:
    Human
  • 宿主来源:
    Mouse
  • 实验应用:
    IHC-P
  • 靶标/特异性:
  • 同种型:
    Mouse IgG1
  • 推荐稀释度:
  • 免疫原:
    Recombinant full-length protein was used as the immunogen for the Alpha Tropomyosin antibody.
  • 免疫原种属:
  • 克隆性:
    Monoclonal (mouse origin)
  • 克隆号:
  • 纯化方式:
    Protein A/G affinity
  • 偶联:
  • 产品浓度:
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    Aliquot the Alpha Tropomyosin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 运输温度:
  • 细胞定位:
  • 预期分子量:
  • 产品形式:
  • 存储溶液:
    0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
  • 有效期:
  • 产地:
    美国
  • 外观:
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  • URL:
  • 灵敏度:
  • 检测范围:
  • 检测方法:
  • 样本类型:
    0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
  • 产品特点:
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  • 分子式:
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