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Estrogen Inducible Protein pS2 / TFF1 Antibody
品牌： NSJ Bio
产品货号： V4400-100UG
规格： 100 ug

报价：
折后价：

数量： - +
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  • 产品名称:
    Estrogen Inducible Protein pS2 / TFF1 Antibody
  • 别名:
  • 产品描述:
    It recognizes a polypeptide of 6.5kDa, identified as pS2 estrogen-regulated protein. Its epitope is located in the c-terminus of human pS2 protein. pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intra-chain disulfide bonds, forming the trefoil motif, or P-domain. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. About 60% of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. pS2 is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract. Several studies have shown that pS2 is primarily expressed in estrogen receptor-positive breast tumors and it may define a subset of estrogen-dependent tumors that displays an increased likelihood of response to endocrine therapy.
  • 反应种属:
    Human
  • 宿主来源:
    Mouse
  • 实验应用:
    IHC-P
  • 靶标/特异性:
  • 同种型:
    Mouse IgG1, kappa
  • 推荐稀释度:
  • 免疫原:
    A recombinant partial protein sequence (within amino acids 1-84) from the human protein was used as the immunogen for the Estrogen Inducible Protein pS2 antibody.
  • 免疫原种属:
  • 克隆性:
    Monoclonal (mouse origin)
  • 克隆号:
  • 纯化方式:
    Protein A/G affinity
  • 偶联:
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  • 保存温度:
    Aliquot the Estrogen Inducible Protein pS2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 运输温度:
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  • 存储溶液:
    0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
  • 有效期:
  • 产地:
    美国
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  • 样本类型:
    0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
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