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T-bet Antibody / Tbox-bet / TBX21
品牌： NSJ Bio
产品货号： V4514-20UG
规格： 20 ug

报价：
折后价：

数量： - +
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  • 产品名称:
    T-bet Antibody / Tbox-bet / TBX21
  • 别名:
  • 产品描述:
    T helper (Th) lymphocytes differentiate into two unique subsets, Th1 and Th2, which differ both in function and in the cytokines they secrete. Th1 and Th2 cytokines promote the growth and differentiation of their subset, and inhibit the growth and differentiation of the opposing subset. T-bet (T-box expressed in T cells) is a Th1-specific T-box transcription factor that controls the expression of the Th1 cytokine, IFN-g. T-bet also converts effector Th2 cells into the opposing Th1 subset. T-bet is selectively expressed in Th1 cells. The level of T-bet expression is increased by signals mediated by the T cell receptor (TCR). IL-12 also induces an increase in the level of T-bet. T-bet was originally isolated from nuclear extracts of resting and PMA/ionomycin-activated AE7 cells. It is expressed in low levels in AE7 cells, and in increased levels in stimulated AE7.
  • 反应种属:
    Human
  • 宿主来源:
    Mouse
  • 实验应用:
    IHC-P
  • 靶标/特异性:
  • 同种型:
    Mouse IgG1, kappa
  • 推荐稀释度:
  • 免疫原:
    A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the TBX21 antibody.
  • 免疫原种属:
  • 克隆性:
    Monoclonal (mouse origin)
  • 克隆号:
  • 纯化方式:
    Protein A/G affinity
  • 偶联:
  • 产品浓度:
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    Aliquot the TBX21 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 运输温度:
  • 细胞定位:
  • 预期分子量:
  • 产品形式:
  • 存储溶液:
    0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
  • 有效期:
  • 产地:
    美国
  • 外观:
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  • 功能与背景:
  • URL:
  • 灵敏度:
  • 检测范围:
  • 检测方法:
  • 样本类型:
    0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
  • 产品特点:
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  • 分子式:
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  • PubChem CID:
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