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N-Cadherin Antibody / CDH2
品牌： NSJ Bio
产品货号： V4538SAF-100UG
规格： 100 ug

报价：
折后价：

数量： - +
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  • 产品名称:
    N-Cadherin Antibody / CDH2
  • 别名:
  • 产品描述:
    Recognizes a protein of ~140kDa, identified as N-Cadherin (NCAD), also known as CD325. NCAD is a member of the Cadherin superfamily, and consists of five extracellular repeats, a transmembrane domain and a cytoplasmic domain. CD325 deficient mice die at day 10 of gestation and embryos display major heart defects and malformed neural tubes and somites. Consistent with this, CD325 has been implicated in several aspects of cardiac development including the precardiac mesoderm, establishment of left-right symmetry and cardiac looping morphogenesis. Furthermore, CD325 is normally involved in inducing cell cycle arrest and its expression is frequently deregulated in cancer cells. Studies have linked N-cadherin to cancer metastasis by showing the aggressive tumor cells had preferentially turned on N-cadherin as opposed to E- or P-cadherin.
  • 反应种属:
    Human
  • 宿主来源:
    Rabbit
  • 实验应用:
    IHC-P
  • 靶标/特异性:
  • 同种型:
    Rabbit IgG, kappa
  • 推荐稀释度:
  • 免疫原:
    A recombinant partial protein sequence (within amino acids 605-905) from the human protein was used as the immunogen for the N-Cadherin antibody.
  • 免疫原种属:
  • 克隆性:
    Recombinant Rabbit Monoclonal
  • 克隆号:
  • 纯化方式:
    Protein A/G affinity
  • 偶联:
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  • 保存温度:
    Aliquot the N-Cadherin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 运输温度:
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  • 产品形式:
  • 存储溶液:
    1 mg/ml in 1X PBS; BSA free, sodium azide free
  • 有效期:
  • 产地:
    美国
  • 外观:
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  • 灵敏度:
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  • 检测方法:
  • 样本类型:
    1 mg/ml in 1X PBS; BSA free, sodium azide free
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