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Ganglioside GT1a Monoclonal Antibody (Clone CGM5)
品牌： Cayman
产品货号： 38288
规格： 500 µg

报价：
折后价：

数量： - +
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  • 产品名称:
    Ganglioside GT1a Monoclonal Antibody (Clone CGM5)
  • 别名:
    GT1a|Trisialoganglioside GT1a
  • 产品描述:
    Ganglioside GT1a is a trisialoganglioside and sphingolipid.{72232} It is characterized by having two sialic acid residues linked to the terminal galactose, unlike ganglioside GT1b (Item Nos. 31592 | 15588 | 31712), which has two sialic residues linked to the inner galactose unit, and is expressed in the brain and in motor endplates of extraocular neuromuscular junctions.{72232,72233} Ganglioside GT1a is similar in shape to lipo-oligosaccharides (LOS) on the membranes of certain pathogens, including C. jejuni and H. influenzae.{72235} Due to this similarity, autoantibodies against ganglioside GT1a can be formed during C. jejuni or H. influenzae infection. These autoantibodies have been found in patients with the acute paralytic disease Guillain-Barré syndrome, including those with the pharyngeal-cervical-brachial regional variant.{72235,72236} Levels of ganglioside GT1a are increased in grade I dysembryoplastic neuroepithelial tumors but decreased in high-grade peripheral primitive neuroectodermal tumors and ependymomas compared with non-cancerous brain tissue.{72234} Cayman’s Ganglioside GT1a Monoclonal Antibody (Clone CGM5) can be used for dot blot, ELISA, immunofluorescence (IF), and TLC immunostaining applications.
  • 反应种属:
  • 宿主来源:
    Mouse
  • 实验应用:
    Dot blot, ELISA, IF, TLC immunostaining
  • 靶标/特异性:
  • 同种型:
    IgM
  • 推荐稀释度:
  • 免疫原:
    C. jejuni (OH4382)
  • 免疫原种属:
  • 克隆性:
  • 克隆号:
    CGM5
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  • 阳性对照:
  • 保存温度:
    -20
  • 运输温度:
    -20
  • 细胞定位:
  • 预期分子量:
  • 产品形式:
    500 µg of mouse IgM in a concentrated hybridoma supernatant
  • 存储溶液:
  • 有效期:
    365
  • 产地:
    美国
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