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Ganglioside GQ1b Monoclonal Antibody (Clone EM6)
品牌： Cayman
产品货号： 38291
规格： 100 µg

报价：
折后价：

数量： - +
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  • 产品名称:
    Ganglioside GQ1b Monoclonal Antibody (Clone EM6)
  • 别名:
    GQ1b|Tetrasialoganglioside GQ1b
  • 产品描述:
    Ganglioside GQ1b is a sialic acid-containing glycosphingolipid that has been found in myelin of the oculomotor nerves and dorsal root ganglia, as well as neuromuscular spindle fibers.{69575,69574} It is found on the plasma membrane, where it is anchored by the ceramide moiety with the sialylated oligosaccharide on the extracellular side.{69575} In axonal myelin, it helps to stabilize the paranodal region in the node of Ranvier.{69574} Ganglioside GQ1b is similar in shape to lipo-oligosaccharides (LOS) on the membrane of certain pathogens, including the bacterium C. jejuni. Due to this similarity, autoantibodies against ganglioside GQ1b can be formed during infection with C. jejuni. Autoantibodies against ganglioside GQ1b are found in the cerebrospinal fluid in a majority of patients during the acute phase of Miller-Fisher syndrome, a rare variant of Guillain-Barré syndrome characterized by eye movement abnormalities, impaired coordination, and tendon reflex loss.{69575,69576,69574} Cayman's Ganglioside GQ1b Monoclonal Antibody (Clone EM6) can be used for dot blot, ELISA, immunofluorescence (IF), and TLC immunostaining applications.
  • 反应种属:
  • 宿主来源:
    Mouse
  • 实验应用:
    Dot blot, ELISA, IF, TLC immunostaining
  • 靶标/特异性:
  • 同种型:
    IgM
  • 推荐稀释度:
  • 免疫原:
    Ganglioside GQ1b liposomes
  • 免疫原种属:
  • 克隆性:
  • 克隆号:
    EM6
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  • 阳性对照:
  • 保存温度:
    -20
  • 运输温度:
    -20
  • 细胞定位:
  • 预期分子量:
  • 产品形式:
    100 µg of mouse IgM in a concentrated hybridoma supernatant
  • 存储溶液:
  • 有效期:
    365
  • 产地:
    美国
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