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产品名称:
anti-FLIP, mAb (Dave-2)
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别名:
I-FLICE; CLARP; CASPER; Usurpin, CASH; FLAME-1
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产品描述:
FLIP is an apoptosis regulator protein which functions as a crucial link between cell survival and cell death pathways in mammalian cells and acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. FLIP lacks enzymatic (caspase) activity. FLIP is highly expressed in skeletal muscle, pancreas, heart, kidney, placenta and peripheral blood leukocytes.
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反应种属:
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宿主来源:
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实验应用:
IP, WB
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靶标/特异性:
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同种型:
Rat IgG2a
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推荐稀释度:
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免疫原:
Recombinant human FLIP (aa 1-480).
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免疫原种属:
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克隆性:
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克隆号:
Dave-2
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纯化方式:
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偶联:
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产品浓度:
1 mg/ml
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表达系统:
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阳性对照:
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保存温度:
-20°C
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运输温度:
BLUE ICE
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细胞定位:
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预期分子量:
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产品形式:
liquid
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存储溶液:
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
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有效期:
Stable for at least 1 year after receipt when stored at -20°C.
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产地:
瑞士
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外观:
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URL:
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灵敏度:
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检测方法:
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样本类型:
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
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产品特点:
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纯度:
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生物活性:
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内毒素水平:
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PubChem CID: