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产品名称:
anti-RIG-I, mAb (Alme-1)
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别名:
RIG-1; Retinoic Acid-inducible Gene 1 Protein; DEAD-box Protein 58; Probable ATP-dependent RNA Helicase DDX58
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产品描述:
RIG-I and MDA5 are highly conserved helicases involved in the innate immune response to virus. RIG-I is a member of the DEAD-box RNA helicases and is activated by cytoplasmic dsRNA and 5’-ppp RNA produced during the viral replication. The protein is characterized by a N-terminal region with two caspase recruitment domains (CARD) and a C-terminal region harboring potential ATP-dependent RNA helicase activity. RIG-I recruits the CARD adaptor inducing IFN-beta (Cardif) in a CARD-CARD-dependent manner resulting in NF-kappaB and IRF3 activation.
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反应种属:
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宿主来源:
Purified from concentrated hybridoma tissue culture supernatant.
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实验应用:
IHC, IP, WB
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靶标/特异性:
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同种型:
Mouse IgG1
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推荐稀释度:
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免疫原:
Recombinant human RIG-I (aa 201-713).
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免疫原种属:
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克隆性:
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克隆号:
Alme-1
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纯化方式:
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偶联:
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产品浓度:
1mg/ml
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表达系统:
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阳性对照:
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保存温度:
+4°C
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运输温度:
BI
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细胞定位:
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预期分子量:
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产品形式:
liquid
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存储溶液:
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
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有效期:
Stable for at least 1 year after receipt when stored at -20°C.
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产地:
瑞士
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外观:
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功能与背景:
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URL:
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灵敏度:
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检测范围:
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检测方法:
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样本类型:
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
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产品特点:
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纯度:
>95% (SDS-PAGE)
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生物活性:
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内毒素水平:
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表达方式:
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溶解度:
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PubChem CID: