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产品名称:
anti-ZBP1, mAb (Zippy-1)
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别名:
Z-DNA-binding Protein 1; Tumor Stroma and Activated Macrophage Protein DLM-1; DNA-dependent Activator of IFN-regulatory Factors; DAI
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产品描述:
ZBP1 is an interferon inducible protein that binds to cytoplasmic DNA and plays a role in host defense against tumors and pathogens. ZBP1 is highly expressed in lymphatic tissues including lymph node, leukocytes, tonsil, bone marrow and spleen. ZBP1 is an innate immune sensor of Influenza A virus (IAV). ZBP1 regulates NLRP3 (nucleotide and oligomerization domain, leucine-rich repeat-containing protein family, pyrin domain containing 3) inflammasome activation as well as induction of different types of cell death (apoptosis, necroptosis and pyroptosis) during IAV infection.
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反应种属:
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宿主来源:
Purified from concentrated hybridoma tissue culture supernatant.
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实验应用:
ICC, IP, WB
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靶标/特异性:
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同种型:
Mouse IgG2a
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推荐稀释度:
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免疫原:
Recombinant mouse ZBP1 (aa 1-411).
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免疫原种属:
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克隆性:
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克隆号:
Zippy-1
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纯化方式:
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偶联:
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产品浓度:
1mg/ml
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表达系统:
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阳性对照:
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保存温度:
+4°C
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运输温度:
BI
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细胞定位:
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预期分子量:
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产品形式:
liquid
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存储溶液:
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
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有效期:
Stable for at least 1 year after receipt when stored at -20°C.
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产地:
瑞士
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外观:
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URL:
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灵敏度:
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检测方法:
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样本类型:
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
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产品特点:
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纯度:
>95% (SDS-PAGE)
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生物活性:
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