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anti-PSD-95 (palmitoylated), mAb (rec.) (PF11)
品牌: Adipogen
产品货号: AG-27B-0021-C100
规格: 100 ug

报价:
折后价:

数量: - +
产品详情
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  • 产品名称:
    anti-PSD-95 (palmitoylated), mAb (rec.) (PF11)
  • 别名:
    PSD95; Disks Large Homolog 4; DLG4; Postsynaptic Density Protein 95; Synapse-associated Protein 90; SAP90
  • 产品描述:
    PSD-95 is a member of proteins located at a specialized postsynaptic membrane region, called the postsynaptic density (PSD). PSD-95 is the most abundant scaffold protein specifically enriched in the PSD. It contains three PDZ domains, an SH3 domain and a guanylate kinase (GuK)-like domain. Through its PDZ domains, PSD-95 assembles various synaptic components at the PSD including intracellular signaling molecules (e.g. SynGAP and kalirin-7), ion channels (e.g. stargazin/AMPA receptors [AMPARs] and NMDA receptors) and cell adhesion molecules (e.g. neuroligin). PSD-95 plays a primary role in synaptic development and maturation and is regulated by palmitoylation at its N-terminal cysteine residues leading to its postsynaptic targeting. Palmitoylation of PSD-95 is triggered by DHHC2, a plasma membrane-inserted palmitoylating enzyme. Palmitoylated PSD-95 is almost exclusively localized at excitatory synapses in neurons.
  • 反应种属:
  • 宿主来源:
    Produced without the use of animals. Purified from HEK 293 cell culture supernatant.
  • 实验应用:
    ICC, IHC
  • 靶标/特异性:
  • 同种型:
    Human IgG2
  • 推荐稀释度:
  • 免疫原:
    Palmitoylated PSD-95.
  • 免疫原种属:
  • 克隆性:
  • 克隆号:
    PF11
  • 纯化方式:
  • 偶联:
  • 产品浓度:
    0.5 mg/ml
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    -20°C
  • 运输温度:
    BLUE ICE
  • 细胞定位:
  • 预期分子量:
  • 产品形式:
    liquid
  • 存储溶液:
    Liquid. In PBS containing 10% glycerol.
  • 有效期:
    Stable for at least 1 year after receipt when stored at -20°C.
  • 产地:
    瑞士
  • 外观:
  • 生产商:
  • 功能与背景:
  • URL:
  • 灵敏度:
  • 检测范围:
  • 检测方法:
  • 样本类型:
    Liquid. In PBS containing 10% glycerol.
  • 产品特点:
  • 纯度:
    >95% (SDS-PAGE)
  • 生物活性:
  • 内毒素水平:
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  • 分子式:
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  • PubChem CID:
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