anti-Acetyl-Histone H2B (Lys20), Rabbit Monoclonal (RM235) - 深圳欣博盛生物科技有限公司

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anti-Acetyl-Histone H2B (Lys20), Rabbit Monoclonal (RM235)

品牌： Adipogen

产品货号： REV-31-1113-00-C100

规格： 100 µg

报价：

折后价：

数量： - +

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产品名称:

anti-Acetyl-Histone H2B (Lys20), Rabbit Monoclonal (RM235)
别名:

H2B K20ac
产品描述:

Histones are proteins that package DNA into nucleosomes. Histones are responsible for maintaining the shape and structure of a nucleosome. One chromatin molecule is composed of at least one of each core histones per 100 base pairs of DNA. There are five families of histones known to date; these histones are termed H1/H5, H2A, H2B, H3, and H4. H2B is considered a core histone, along with H2A, H3 and H4. H2A packages DNA molecules into chromatin and has been correlated with DNA modification and epigenetics. H2A plays a major role in determining the overall structure of chromatin and regulates gene expression. Protein modification on histone H2A exist and can sometimes result in a change in function. Different H2A variants were exploited to have different functions, genetic sequences and modifications. Histone H2B is a structural protein that helps organize eukaryotic DNA. It plays an important role in the biology of the nucleus where it is involved in the packaging and maintaining of chromosomes, regulation of transcription and replication and repair of DNA. Histone H2B helps regulate chromatin structure and function through post-translational modifications and specialized histone variants. Hyperacetylation of histone tails helps DNA-binding proteins access chromatin by weakening histone-DNA and nucleosome-nucleosome interactions. Acetylation of a specific lysine residue binds to bromine-containing domains of certain transcription and chromatin regulatory proteins. This docking facilitates the recruitment of these proteins to the correct region of the chromosome. Ubiquitinated histone H2B is often found in regions of active transcription and stimulates transcriptional elongation and sets the stage for further modifications that regulate multiple elements of transcription. In histone H2B, a phosphorylated serine or threonine residue activates transcription.
反应种属:
宿主来源:

Rabbit
实验应用:

ELISA, ICC, WB, Multiplex
靶标/特异性:
同种型:

Rabbit IgG
推荐稀释度:
免疫原:

An acetyl-peptide corresponding to Acetyl-Histone H2B (Lys20).
免疫原种属:
克隆性:
克隆号:

RM235
纯化方式:
偶联:
产品浓度:

1 mg/ml
表达系统:
阳性对照:
保存温度:

-20°C
运输温度:

BLUE ICE
细胞定位:
预期分子量:
产品形式:

liquid
存储溶液:

Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
有效期:

Stable for at least 1 year after receipt when stored at -20°C.
产地:

瑞士
外观:
生产商:
功能与背景:
URL:
灵敏度:
检测范围:
检测方法:
样本类型:

Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
产品特点:
纯度:

Protein A purified.
生物活性:
内毒素水平:
来源:
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Accession #:
CAS号:
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PubChem CID: