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anti-Alpha Cardiac Actin, Rabbit Monoclonal (RM257)
品牌： Adipogen
产品货号： REV-31-1138-00-R100
规格： 100 µl

报价：
折后价：

数量： - +
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  • 产品名称:
    anti-Alpha Cardiac Actin, Rabbit Monoclonal (RM257)
  • 别名:
    ACTC1
  • 产品描述:
    Actins are a family of globular multi-functional proteins that form microfilaments and are important for cell movement and the tensing (contraction) of muscles. ACTC1 (Cardiac alpha actin) together with regulatory proteins tropomyosin and 3 troponins (C, I, and T) forms the thin contractile filament, in turn connecting the myocellular Z-disc with the thick filament protein myosin. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC). Mutations in ACTC1 are associated in autosomal dominant heart failure and familial atrial septal defect (ASD). Cardiac (ACTC1) and skeletal (ACTA1) alpha actins differ by only four amino acids (Asp4Glu, Glu5Asp, Leu301Met, Ser360Thr; cardiac/skeletal).
  • 反应种属:
  • 宿主来源:
    Rabbit
  • 实验应用:
    IHC, WB
  • 靶标/特异性:
  • 同种型:
    Rabbit IgG
  • 推荐稀释度:
  • 免疫原:
    A synthetic peptide corresponding to the N-terminus of human alpha-cardiac actin.
  • 免疫原种属:
  • 克隆性:
  • 克隆号:
    RM257
  • 纯化方式:
  • 偶联:
  • 产品浓度:
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    -20°C
  • 运输温度:
    BLUE ICE
  • 细胞定位:
  • 预期分子量:
  • 产品形式:
    liquid
  • 存储溶液:
    Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
  • 有效期:
    Stable for at least 1 year after receipt when stored at -20°C.
  • 产地:
    瑞士
  • 外观:
  • 生产商:
  • 功能与背景:
  • URL:
  • 灵敏度:
  • 检测范围:
  • 检测方法:
  • 样本类型:
    Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
  • 产品特点:
  • 纯度:
    Protein A purified.
  • 生物活性:
  • 内毒素水平:
  • 来源:
  • 表达方式:
  • Accession #:
  • CAS号:
  • 分子式:
  • 溶解度:
  • PubChem CID:
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